Posts in Sex Chromosomes
New lab preprints!

Exciting to see these new preprints online:

Kelsie’s first chapter of her dissertation - super proud of this one! https://doi.org/10.1101/2021.07.08.451646

An amazingly fun project with the awesome Mollie Manier: https://www.biorxiv.org/content/10.1101/2021.11.15.468624v1

A new paper on disrupted X chromosome expression in sterile mouse hybrids: https://www.biorxiv.org/content/10.1101/2021.11.12.468424v1

And two impressive collaborations led by the Good Lab at the University of Montana from Emily Kopania: https://www.biorxiv.org/content/10.1101/2021.08.04.455131v2 and from Emily Moore: https://www.biorxiv.org/content/10.1101/2021.11.15.468705v2

Our new review in Trends in Genetics

Spermatogenesis and the Evolution of Mammalian Sex Chromosomes

Erica L. Larson, Emily E.K. Kopania, and Jeffrey M. Good  

Developmental constraint and sexual conflict shape the evolution of hetero- morphic sex chromosomes. These contrasting forces are perhaps strongest during spermatogenesis in species with XY males. In this review, we consider how the unique regulatory environment and selective pressures of spermato- genesis interact to impact sex chromosome evolution in mammals. We explore how each developmental phase of spermatogenesis influences sex chromo- some gene content, structure, and rate of molecular evolution, and how these attributes may contribute to speciation. We argue that a developmental context is fundamental to understanding sex chromosome evolution and that an evolutionary perspective can shed new light on our understanding of sperm development. PAPER

 
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